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ICSI is a similar procedure as conventional IVF where fertility expert will collect the eggs and sperm of each partner. The only difference between the two procedures is the method of fertilization.
In conventional IVF, the fertility expert of your will mix together the eggs and sperm in a dish and the sperm fertilizes the egg naturally. However, there are chances that egg will fertilize naturally but for this large numbers of actively swimming normal sperm are required. In many cases, the number of available suitable sperm may be very limited or there may be other factors that prevent fertilization, in such condition IVF is not the best option. Your fertility expert will suggest ICSI treatment Nepal which provides you a hope to have your own baby.
ICSI is a laboratory procedure where your fertility expert will pick up the men single sperm with a fine glass needle and directly injected into each egg of a woman. This procedure is performed by the highly skilled and experienced embryologist in the laboratory where he/she use specialist equipment. In this procedure, very few sperms are required and the ability of the sperm to penetrate the egg is no longer required as this has been assisted by the ICSI technique. ICSI procedure does not guarantee that fertilization is going to happen as normal, however, still need to occur once the sperm has been placed in the egg.
How the Sperms are Retrieving to Use in ICSI Procedure?
The fertility expert will retrieve the sperms through normal ejaculation for those male members who have low sperm count or sperm with low mobility. In case, a man has had a vasectomy, the microsurgical vasectomy reversal is the most cost-effective option for restoring his fertility.
When a competent microsurgical vasectomy reversal has failed or the man refuses surgery then the needle aspiration or microsurgical sperm retrieval are good alternatives. Needle aspiration allows the fertility expert to obtain easily and quickly the adequate numbers of sperm for the ICSI procedure. They use a tiny needle to extract sperm directly from the men testis.
Needle aspiration is a simple procedure which is performed under sedation with minimal discomfort; however, there are chances for pain and swelling afterward. The sperm that has been obtained from testis is only an appropriate procedure for ICSI when testicular sperm is not able to penetrate an egg by itself.
When the ICSI Procedure is Recommended?
ICSI is a procedure which may be recommended when there is no difficulty in achieving fertilization. ICSI is a treatment which is most often used for couples who are dealing with male infertility factors. A male infertility factor includes any of the below following:
- Low sperm counts
- Poor motility or movement of the sperm
- The quality of sperms is poor
- Sperm that lacks the ability to penetrate an egg
When there are no sperms in the male’s ejaculation that condition is known as azoospermia and there are two types of azoospermia: obstructive and non-obstructive.
Obstructive azoospermia may be caused by any of the following:
- Previous vasectomy
- Congenital absence of the vas
- Scarring from prior infections
Non-obstructive azoospermia occurs when there is no production of sperm from the defective testicle. In the case of azoospermia, the probability of obtaining usable sperm is low, and the possibility of using donor sperm may be considered.
What are the Risks of Using the ICSI Procedure?
ICSI is a procedure which can increase IVF success rates but the procedure is not perfect. The following are some more common risks that are associated with ICSI and these are:
a) Damage to the embryos: Fertilization rates with ICSI range from 50 to 80%. However, it has been found that not all fertilized eggs develop into healthy embryos due to which some eggs and embryos do become damaged during the ICSI procedure.
b) Becoming pregnant with the multiple eggs: As we all know, that ICSI takes place as part of the IVF process, hence, there are increased chances of becoming pregnant with multiple eggs for couples who are undergoing for the ICSI procedure. Couples that use ICSI with IVF have about a 35 to 45% chance to have twins and 10 to 15% chance of having triplets or more.
According to the study, if you carry the multiple pregnancies then it will increase your chances of developing the following complications during pregnancy and childbirth which includes:
- Gestational diabetes
- High blood pressure
- Low amniotic fluid levels
- Bed rest
- Cesarean section or premature labor
When you get pregnant with multiples, your babies are also at the higher risk for complications, such as being born prematurely with low birth weight, or they face difficulty while breathing on their own due to immature lungs. These conditions are more susceptible to infections.
c) Birth defects: According to the study, the birth defects with ICSI and IVF lead to a similar percentage as babies are conceived naturally. However, the risk with ICSI procedure of having a baby with abnormalities is very minimal which less than 1% is.
ICSI Treatment Costs in Nepal?
ICSI is a treatment which fertility experts perform to treat male infertility issues and the estimated cost for treating male infertility depend on the procedure. There are other options also available to treat male infertility apart from ICSI treatment and these are as follows with their costs:
- IUI is the first line treatment which costs around 50,000NPR Or USD 1,000 for one cycle, however, if the couple requires the ovulation induction, medications, and other screenings which will increase the treatment cost which goes up to Or 3,40 ,000 NPR
- The cost of ICSI treatment with IVF is around 4, 00,000 NPR OR USD 5500 for one cycle without including medications. ICSI with IVF is the best fertility treatment which increases the chances of conception as compared to IVF alone. In case, the couple needs ICSI with IVF with medications than the cost of the treatment go up to USD 7,000 for the fresh cycle.
- If you are using egg or sperm donor to increase your chances of conception than the cost of the treatment is around 2, 00,000 NPR for Egg Donors & Sperm Donor 50,000 NPR or USD Amount 20,000.