Testicular Biopsy

Testicular Biopsy is a one of the treatments for male infertility and involves the process of taking a sample of tissue from the testicles for the analysis in the laboratory. Basically, the two testicles are the reproductive organs among the males that produce the sperms and the male’s reproductive hormones called “testosterone”. These testicles are located in the scrotum region, that is a soft fleshy pouch of the tissue which is used to hang the male’s penis.

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Testicular is done for whom and why?

Testicular biopsy is done rarely and when it is done it is done to help determine the cause of  male infertility. Testicular biopsy is done when the two these conditions are there:

  • The man’s semen does not have sperm.
  • Hormone test results are within the normal range.

And is used for the diagnosis of the following:

  • To diagnose the location and condition of a lump in the testes
  • To diagnose causes of male infertility
  • To obtain sperm for in vitro fertilization (IVF)

Types of testicular Biopsy

There are two types of testicular Biopsy.

Percutaneous Biopsy: In this a thin biopsy needle is inserted through the skin. The needle has a syringe on the end to collect the testicular tissue. This procedure does not require an incision or stitches. Also referred to as fine needle biopsy.
Open Biopsy: Also referred to as the surgical biopsy. The doctor starts by making a cut in the skin. A cut is also made in the testicle. Then a small tissue sample is taken from the opening and stitches are used to close the cuts.

Preparation for the Testicular Biopsy

Before having a testicular biopsy, One needs to tell your doctor if you:

  • Have had any bleeding problems.
  • Are allergic to any medicines, including anesthetics.
  • Take any medicines regularly. Be sure your doctor knows the names and doses of all your medicines…

If a testicular biopsy is done using local anesthesia, no specific preparation is needed. And If the biopsy is done using general anesthesia, your doctor will inform how long  before surgery you need to stop eating and drinking. Instructions need to be followed very seriously otherwise the surgery might be canceled. During biopsy preparation, an intravenous line (IV) is inserted in your arm, and a sedative medicine is given about an hour before the biopsy.

Recovery from a Testicular Biopsy

Once the Testicular Biopsy is done, some special instructions need to be followed to heal fast and comfortably. Basic Instruction that is advised involves:

  • To refrain from sexual activity for one to two weeks
  • To wear an athletic supporter for several days
  • To keep the site of the biopsy dry, and avoid washing it for several days
  • To avoid aspirin for one week
  • To use acetaminophen for soreness

Risks of a Testicular Biopsy

There is a slight risk of bleeding or infection. The area may be sore for 2 to 3 days after the biopsy. The scrotum may swell or become discolored. This should clear up within a few days.


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